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Around 10% of pregnant women infected with Covid-19 are at heightened risk of complications (whether symptomatic or not).
We did not know how pandemic service reconfiguration affected outcomes (including costs) in the UK, or how to optimise care post-pandemic. Evidence showed that vaccine hesitancy among pregnant women was high, yet little data existed on use of Covid-19 vaccines in pregnancy planning, pregnancy, or breastfeeding.

In two south London NHS trusts providing maternity care (Guy’s and St Thomas’ and King’s College Hospital NHS Foundation Trusts), the research team aimed to study the impact on women and babies of Covid-19 pandemic-related maternity service configurations — virtual care, out-of-office monitoring and vaccination — particularly for those from minority ethnic groups or living socially or medically complex lives.
Quantitative — describe, quantify and explain
For all pregnancies, study the impact on maternity care quality (effectiveness, safety, and acceptability), maternal and offspring outcomes, and costs within the context of service configurations, particularly: virtual consultations; out-of-office monitoring (e.g. patient-reported blood pressure); and Covid-19 vaccination (provision, uptake, and adverse events).
Using routinely-collected, linked maternity, mental health, and offspring data from the eLIXIR platform (~35,000 records) from South London. Segmented and individual-level multivariate regression analysis.
Social science — enrich understanding
In-depth interviews with up to 105 pregnant/postpartum women, partners, care providers and policymakers with lived experience of maternity services during the pandemic, with a focus on those from ethnic minority groups, with medical/mental health co-morbidities, or living with social complexity.
Also questionnaires administered nationally (~43,000 maternity service users) via the Covid Symptom Study (CSS) Biobank to understand vaccine uptake, hesitancy and side effects.
Stakeholder engagement — policy action
Regional listening events (‘Imagining our best future’) in each UK nation to assess WP1 and WP2 findings, brainstorm and prioritise high-impact future actions, and understand barriers to implementation. Followed by a National Policy Lab (‘co-production for action’) to produce an ‘Imagine our best future’ report.
PPIE was embedded throughout the project proposal development and continued throughout the project:
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Service users and south London community
31 South London service users with experience of maternity care during the pandemic joined interviews or focus groups. Minority ethnic group members and those living with social or medical complexity were represented. Concerns about digital poverty prompted inclusion of relevant support in the budget.
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Networks and engagement organisations
Collaborative working with voluntary sector organisations, social media networks, individual women, and the ARC South London Maternity and Perinatal Mental Health PPIE Advisory Group.
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PPIE Advisory Group
Met every four months to assist information-sharing and facilitate research co-production. Members synthesise PPIE results, write PPIE sections of reports and blogs, and contribute to the design of guides.
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Support and learning
Trauma-informed ways of working accomplished through training with Birth Companions Charity. Group pre-meetings and personal follow-up provided for service users’ comfort.
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Impact and governance
Core team reported back at each Advisory Group meeting on how feedback influenced the research. PPIE voices appropriately resourced, regularly reviewed and reported on.
The pandemic forced NHS maternity services to undergo substantial change. While harms were evident, there are also potential positives — an opportunity to ‘build back better’ while there is political will for data-driven reform:
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New ways of working that may facilitate equity of access to maternity care
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Better targeting of services based on evidence
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Cost reduction from health system and patient perspectives (virtual vs face-to-face care) and improved acceptability
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Professor of women’s health, King’s College London (project lead) |
Senior postdoctoral research fellow, King’s College London |
PPIE consultant and ARC theme PPIE lead |
Research associate in social science of women’s health, KCL |
Original source: arc-sl.nihr.ac.uk — NIHR ARC South London legacy content archived May 2026.